Status | Study |
Completed |
Study Name: Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy Condition: Leber Hereditary Optic Neuropathy Date: 2014-06-25 Interventions: Drug: cyclosporine |
Recruiting |
Study Name: Safety Study of an Adeno-associated Virus Vector for Gene Therapy of Leber's Hereditary Optic Neuropathy Condition: Leber's Hereditary Optic Neuropathy Date: 2014-06-06 Interventions: Drug: injection of scAAV2-P1ND4v2 5.00x10e9 vg (Low), |
Active, not recruiting |
Study Name: Safety Evaluation of Gene Therapy in Leber Hereditary Optic Neuropathy (LHON) Patients Condition: Leber Hereditary Optic Neuropathy Date: 2014-02-13 Interventions: Genetic: GS010 |
Completed |
Study Name: Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease Condition: Inherited Mitochondrial Disease, Including Leigh Syndrome Date: 2013-12-17 Interventions: Drug: Cysteamine Bitartrate Cysteamine Bitartrate Delayed-release Capsules |
Completed |
Study Name: Leber Hereditary Optic Neuropathy (LHON) Historical Case Record Survey Condition: Leber Hereditary Optic Neuropathy (LHON) Date: 2013-06-26 |
Withdrawn |
Study Name: Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON) Condition: Leber's Hereditary Optic Neuropathy Date: 2011-12-16 Interventions: Drug: Idebenone Drug: Placebo |
Completed |
Study Name: RHODOS Follow-up Single-visit Study Condition: Leber's Hereditary Optic Neuropathy Date: 2011-08-19 |
Terminated |
Study Name: Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON) Condition: Leber's Hereditary Optic Neuropathy (LHON) Date: 2011-07-06 Interventions: Device: Near-infrared light-emitting diode (NIR-LED) therapy (Med Light 630 PRO (Medical Devices Inc.)) |
Completed |
Study Name: Safety and Efficacy Study of rAAV2-ND4 Treatment of Leber Hereditary Optic Neuropathy (LHON) Condition: Leber Hereditary Optic Neuropathy Date: 2010-12-27 Interventions: Drug: rAAV2-ND4 injection Other Name: rAAV2-ND4 gene |
Completed |
Study Name: Safety Study of a Single IVT Injection of QPI-1007 in Chronic Optic Nerve Atrophy and Recent Onset NAION Patients Condition: Optic Atrophy Non-arteritic Anterior Ischemic Optic Neuropathy Date: 2010-02-04 Interventions: Drug: QPI-1007 at various doses Single Intravitreal Injection |